ea0037gp.13.01 | Diabetes and obesity – Translational cardiovascular and obesity | ECE2015
Dranse Helen J
, Rourke Jillian L
, Stadnyk Andrew W
, Sinal Christopher J
Background: Chemerin is a recently identified adipocyte-secreted signalling molecule (adipokine) that regulates adipocyte differentiation, metabolism, and inflammation through activation of the cognate receptor Chemokine-Like Receptor 1 (CMKLR1). Circulating chemerin levels are increased in obese patients as well as in patients with inflammatory bowel disease (IBD) such as Crohns disease and ulcerative colitis. Increased white adipose tissue mass (WAT) and resultant chan...